U

10 Letter Words Starting With IS

There are 155 valid 10 letter words that start with IS, drawn from NWL2023, CSW24, and Words With Friends. Sorted below by score, with the single highest scorer called out.

Highest Scoring 10-Letter Words

US Scrabble (NWL)

isindazole - 20 points

UK Scrabble (CSW)

isindazole - 20 points

Words With Friends

isindazole - 22 points

10 Letter Words (155)

View all words starting with IS

Top 20 Highest-Scoring 10 Letter Words Starting With is

Point values shown for US Scrabble, UK Scrabble, and Words With Friends. The average across this full 155 word list is 47.1 combined points.

Rank Word US Scrabble UK Scrabble WWF Points Total
#1 isabelline 12 12 16 40
#2 isabnormal 14 14 18 46
#3 isacoustic 14 14 17 45
#4 isadnormal 13 13 16 42
#5 isagogical 14 14 18 46
#6 isallobars 12 12 15 39
#7 isatogenic 13 13 16 42
#8 iscariotic 14 14 16 44
#9 ischaemias 17 17 18 52
#10 ischialgia 16 16 18 50
#11 ischialgic 18 18 21 57
#12 ischioanal 15 15 17 47
#13 ischiocele 17 17 19 53
#14 ischuretic 17 17 19 53
#15 iseikonias 14 14 15 43
#16 isentropic 14 14 17 45
#17 isethionic 15 15 16 46
#18 ishmaelite 15 15 16 46
🏆 #19 isindazole 20 20 22 62
#20 islamistic 14 14 17 45

Where 10 Letter Words Fit on the Board

At 10 letters, a word almost always uses your entire rack plus tiles already on the board these are realistically bingo-adjacent plays rather than everyday moves, which is why the list leans heavily on compound and suffixed forms (-nesses, -ation, -izing). If you're looking for words you can play more often, shorter lengths starting with IS will give you far more flexible options try 10 letter words starting with IS for a more practical middle ground.

Frequently Asked Questions

What is the highest-scoring 10 letter word starting with is?

isindazole — worth 62 combined points (US Scrabble: 20, UK Scrabble: 20, Words With Friends: 22).

How many 10 letter words start with is?

155 valid words, combining entries from NWL2023, CSW24, and the Words With Friends dictionary.

Are 10 letter words realistic to actually play?

Only occasionally — you'd need most of your rack plus letters already on the board to reach 10 tiles. They're worth knowing for the rare bingo-extension play, but for regular turns, shorter is words will come up far more often.